During the summers of 2002 and 2003, North America was affectedby its largest-ever outbreaks of arboviral encephalitis. WestNile virus caused 2942 cases of meningitis or encephalitis in2002, with 276 deaths, and 2866 cases in 2003, with 246 deaths.1,2West Nile virus, which in the United States was first detectedin New York in 1999, is one of several mosquito-borne neurotropicmembers of the Japanese encephalitis (JE) serogroup of the genusflavivirus, family Flaviviridae, that cause similar diseasepatterns across the globe (Figure 1 and Table 1). These includeSt. Louis encephalitis virus in the United . . . [Full Text of this Article]
Ecology and Epidemiology
Pathogenesis
Clinical Features
Seizures
Poliomyelitis-Like Paralysis
Parkinsonian Movement Disorders
Diagnosis and Treatment
Future Prospects
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From the Departments of Neurological Science and Medical Microbiology, University of Liverpool, Liverpool, United Kingdom.
Address reprint requests to Dr. Solomon at the Department of Neurological Science, University of Liverpool, Walton Centre for Neurology and Neurosurgery, Liverpool L9 7LJ, United Kingdom, or at tsolomon@liv.ac.uk.
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