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Previous Volume 351:476-486 July 29, 2004 Number 5 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Bipolar disorder is one of the most distinct syndromes in psychiatry and has been described in numerous cultures over the course of history.¹ The unique hallmark of the illness is mania. Mania is, in many ways, the opposite of depression. It is characterized by elevated mood or euphoria, overactivity with a lack of need for sleep, and an increased optimism that usually becomes so extreme that the patient's judgment is impaired. For example, a person with mania may decide to purchase 500 television sets if he or she believes that their price will go up. Drives such as sexual desire . . . [Full Text of this Article]

Definitions

Genetics

Treatment

Acute Mania

Bipolar Depression

Mood Stabilizers and Prophylaxis

Psychological Aspects

Pathophysiology

Neurochemical Studies

Neuroimaging and Neuroanatomical Studies

Mechanism of Action of Lithium and Other Mood Stabilizers

Summary

Source Information

From the Stanley Research Center, Ben Gurion University of the Negev, Beersheba, Israel.

Address reprint requests to Dr. Belmaker at the Beersheba Mental Health Center, P.O. Box 4600, Beersheba, Israel, or at belmaker@bgumail.bgu.ac.il.

Related Letters:

Bipolar Disorder
Gross R., Das A. K., Weissman M. M.
Extract | Full Text | PDF  
N Engl J Med 2004; 351:2454-2455, Dec 2, 2004. Correspondence

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