Although Alexander Fleming discovered penicillin in 1928, thesubstance was largely ignored until scientists at Oxford Universityrediscovered it in the early 1940s. Because of World War II,with its air raids and threat of German invasion, the Oxfordgroup sought help in the United States. The meagerness of thesupplies of penicillin dictated its slow evolution as a chemotherapeuticagent. Its early history involved attempts to synthesize thechemical structure and to invent ways to produce larger quantitiesto meet the rapidly growing demand. As more and more types ofinfections were found to be susceptible to penicillin, it . . . [Full Text of this Article]
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From the Division of Infectious Diseases, University Hospitals of Cleveland, Cleveland.
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