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Volume 351:628-630 August 12, 2004 Number 7
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Sins of Omission — Cancer Research without Informed Consent
Barron H. Lerner, M.D., Ph.D.

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Avir Kagan was an attending physician at Brooklyn's Jewish Chronic Disease Hospital (JCDH) in 1963, when he received a surprising request: Would he participate in an experiment in which live cancer cells were injected into chronically ill patients? Although Kagan said no, some of his colleagues agreed. By 1964, an enormous controversy had erupted, and the hospital's staff was being compared to Nazi physicians who had performed brutal experiments in concentration camps.

How did it happen that 22 patients received injections of cancer cells without their knowledge? On the 40th anniversary of this scandal, what can it teach us about . . . [Full Text of this Article]


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From the Department of Medicine and the Mailman School of Public Health, Columbia University Medical Center, New York.



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