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Previous Volume 351:675-682 August 12, 2004 Number 7 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.

During a routine visit, a 59-year-old woman, who describes herself as a lifetime "worrier" and has a family history of depression, reports having restless sleep, muscle tension, and fatigue. Recently, her anxiety has intensified about her children, her job, and her health, and it is having a negative effect on her family and work life. How should she be treated?

The Clinical Problem

Anxiety disorders . . . [Full Text of this Article]

Coexisting Psychiatric Illnesses

Strategies and Evidence

Diagnosis

Assessment of Depression and Suicide Risk

Therapy

Pharmacotherapy

            Tricyclic Antidepressants

            Selective Serotonin-Reuptake Inhibitors

            Serotonin–Norepinephrine–Reuptake Inhibitors

            Duration of Therapy

            Nonbenzodiazepine Anxiolytic Agents

            Benzodiazepines

Psychotherapy

Areas of Uncertainty

Resistant Generalized Anxiety Disorder

Prevention

Screening

Perinatal Management

Guidelines

Conclusions and Recommendations

Source Information

From the Division of Psychiatry and Medicine, Massachusetts General Hospital, Boston.

Address reprint requests to Dr. Fricchione at the Division of Psychiatry and Medicine, Massachusetts General Hospital, Warren 6, 55 Fruit St., Boston, MA 02114, or at gfricchione@partners.org.

Related Letters:

Generalized Anxiety Disorder
Lavie C. J., Milani R. V., Fricchione G.
Extract | Full Text | PDF  
N Engl J Med 2004; 351:2239, Nov 18, 2004. Correspondence

This article has been cited by other articles:

• Raymond, C. B., Morgan, S. G., Caetano, P. A. (2007). Antidepressant Utilization in British Columbia From 1996 to 2004: Increasing Prevalence but Not Incidence. Psychiatr. Serv. 58: 79-84 [Abstract] [Full Text]  
• Spitzer, R. L., Kroenke, K., Williams, J. B. W., Lowe, B. (2006). A Brief Measure for Assessing Generalized Anxiety Disorder: The GAD-7.. Arch Intern Med 166: 1092-1097 [Abstract] [Full Text]  
• Hall, T. A., McGwin, G. Jr, Searcey, K., Xie, A., Hupp, S. L., Owsley, C., Kline, L. B. (2006). Health-Related Quality of Life and Psychosocial Characteristics of Patients With Benign Essential Blepharospasm. Arch Ophthalmol 124: 116-119 [Abstract] [Full Text]  
• Lavie, C. J., Milani, R. V., Fricchione, G. (2004). Generalized Anxiety Disorder. NEJM 351: 2239-2239 [Full Text]