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Volume 352:1047-1048 March 10, 2005 Number 10
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Medical Mystery Answer: Male Infant with Unusual Weight Gain and Rash

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 by Hartmann, H.
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To the Editor: The medical mystery in the January 20 issue1 involved a seven-month-old boy who had congenital Cushing's syndrome and a severe acneiform rash (Figure 1A), with growth of pubic hair. The child's motor development was grossly delayed. Computed tomography of the abdomen showed a solid mass in the region of the left adrenal gland (Figure 1B). The child's plasma cortisol level was elevated, at 44 mg per deciliter (normal range, 5 to 23), and the testosterone level was 6.06 ng per milliliter (normal range, 0.04 to 0.48). Histologic examination of the mass after excision . . . [Full Text of this Article]




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