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Volume 352:1266-1267 March 24, 2005 Number 12
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Care of the Potential Organ Donor

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by Wood, K. E.
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To the Editor: In their review article on the care of the potential organ donor, Wood et al. (Dec. 23 issue)1 emphasize the importance of the correction of hypovolemia and recommend the use of sodium bicarbonate to treat acidosis. They also remind the reader that hypernatremia in the donor can adversely affect the function of the transplant.

Fluid administration, as part of an early, goal-directed therapy, is beneficial in critical care patients with shock.2 However, there is no evidence to support the use of bicarbonate therapy in the treatment of hypoperfusion-induced acidemia. Alkali therapy does not improve hemodynamics, does not . . . [Full Text of this Article]



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