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Editorial
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Volume 352:1589-1591 April 14, 2005 Number 15
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Does Mild Persistent Asthma Require Regular Treatment?
Leonardo M. Fabbri, M.D.

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 by Boushey, H. A.
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Current national1 and international2 guidelines recommend regularly scheduled treatment with inhaled corticosteroids for patients with mild persistent asthma. This recommendation is supported by solid evidence that such treatment achieves and maintains asthma control.3,4 Although there is not universal agreement,3,5 there are data, reviewed by Vignola, that suggest that continuous suppression of airway inflammation by means of inhaled corticosteroids (referred to as controller therapy) may not only control asthma but also prevent its progression.6

In this issue of the Journal, Boushey et al. challenge this recommendation.7 They compared three treatment protocols in patients with mild persistent asthma. In one protocol, patients . . . [Full Text of this Article]


Source Information

From the Clinica di Malattie dell'Apparato Respiratorio, Università degli Studi di Modena e Reggio Emilia–Policlinico di Modena, Modena, Italy.


Related Letters:

Treatment of Mild Asthma
Berti I., Longo G., Visintin S., Chowdhury B. A., Jenkins C. R., Marks G. B., Reddel H. K., Lee D. K.C., Raghupathy A., Brashier B., Salvi S., Boushey H. A., Israel E., Fabbri L. M.
Extract | Full Text | PDF  
N Engl J Med 2005; 353:424-427, Jul 28, 2005. Correspondence

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