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Volume 352:1610 April 14, 2005 Number 15
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Case 38-2004: A Large Tumor of the Skull

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by Richardson, P. G.
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To the Editor: In Case 38-2004 (Dec. 16 issue),1 Richardson et al. provide an excellent discussion of the treatment options available for patients with multiple myeloma. In my opinion, the diagnostic workup for the patient is missing two important tests that should be done routinely, especially in the setting of oligosecretory and extramedullary myeloma. The first is functional imaging with whole-body positron-emission tomography (PET) scanning.2 In this patient, a PET scan would have helped identify occult sites of plasmacytoma, thus providing an accurate assessment of his tumor burden. The second test is the measurement of monoclonal free light chains in . . . [Full Text of this Article]



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