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Case Records of the Massachusetts General Hospital
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Volume 352:1697-1704 April 21, 2005 Number 16
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Case 12-2005 — A 30-Year-Old Woman with a Mediastinal Mass
Margaret A. Shipp, M.D., Suzanne L. Aquino, M.D., and Nancy Lee Harris, M.D.

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Presentation of Case

Dr. Rameen Beroukhim (Medical Oncology): A 30-year-old woman was admitted to the hospital because of a fever and a mediastinal mass.

The patient had been in her usual state of health until two months before admission, when pain developed in her left shoulder, arm, and chest, without trauma. She was seen by a nurse practitioner at another facility. On examination, there was tightness of the left trapezius muscle and tenderness to palpation along the costochondral junction. She was treated with ibuprofen, heat, and massage and asked to return if the symptoms worsened.

One month before admission, the patient came to . . . [Full Text of this Article]

Differential Diagnosis

Clinical Diagnosis

Dr. Margaret A. Shipp's Diagnosis

Pathological Discussion

Discussion of Management

Anatomical Diagnosis


Source Information

From the Division of Medical Oncology, Dana–Farber Cancer Institute (M.A.S.); the Departments of Radiology (S.L.A.) and Pathology (N.L.H.), Massachusetts General Hospital; and the Departments of Medicine (M.A.S.), Radiology (S.L.A.), and Pathology (N.L.H.), Harvard Medical School.




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