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Previous Volume 352:1920-1922 May 5, 2005 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Colorectal cancer is the third most common cause of death from cancer in the United States, after lung cancer and breast cancer.¹ A well-defined hereditary predisposition accounts for probably 3 to 4 percent of cases of colorectal cancer. Conditions such as familial adenomatous polyposis and the Lynch syndrome (also known as hereditary nonpolyposis colorectal cancer) nevertheless represent important models, and their contribution to the understanding of mechanisms of carcinogenesis is out of proportion to their frequency. Within a family with the Lynch syndrome, opportunities for genetic testing and enhanced surveillance exist. Because of the early age at the onset of . . . [Full Text of this Article]

Source Information

From the Creighton University School of Medicine, Omaha, Nebr. (H.T.L.); and the University of Texas M.D. Anderson Cancer Center, Houston (P.M.L.).

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