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Volume 352:1923-1925 May 5, 2005 Number 18
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Myocardial Stunning Due to Sudden Emotional Stress

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 by Wittstein, I. S.
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To the Editor: Wittstein et al. (Feb. 10 issue)1 report a marked elevation of circulating markers of sympathetic stimulation, including neuropeptide Y, and raise the possibility of direct, catecholamine-induced myocardial stunning. Notable features of this syndrome are a presentation with chest pain and reversible electrocardiographic (ECG) abnormalities, which strongly suggest that severe, persistent myocardial ischemia is a cause of prolonged stunning.

Persistent, deep, negative T waves and reversible Q waves are common in patients with variant angina after very prolonged coronary spasm.2 In persons with stress-induced myocardial stunning, epicardial coronary-artery spasm has been documented angiographically by chance3 and after provocative . . . [Full Text of this Article]




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