FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 352:2014-2016 May 12, 2005 Number 19 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Letters Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear Related Article by Eghbali-Fatourechi, G. Z. PubMed Citation

Bone remodeling is a temporally regulated process resulting in the coordinated resorption and formation of skeletal tissue carried out in basic multicellular units throughout life.¹ Signals determining the fate, function, and ultimate death of cells of the osteoclast and osteoblast lineages define the populations of cells that resorb and form bone in basic multicellular units. There, osteoblasts appear at sites vacated by osteoclasts, a process called coupling. As resorption by osteoclasts is terminated, the resorptive surface is covered by a thin layer of cement, where osteoblasts assemble to form bone and fill the cavity.²

During growth, two types of bone . . . [Full Text of this Article]

Source Information

From the Department of Research, Saint Francis Hospital and Medical Center, Hartford, Conn., and the University of Connecticut School of Medicine, Farmington.

Related Letters:

Circulating Osteoblast-Lineage Cells
Sata M., Tanaka K., Nagai R., Eghbali-Fatourechi G. Z., Khosla S.
Extract | Full Text | PDF  
N Engl J Med 2005; 353:737-738, Aug 18, 2005. Correspondence

This article has been cited by other articles:

• Giustina, A., Mazziotti, G., Canalis, E. (2008). Growth Hormone, Insulin-Like Growth Factors, and the Skeleton. Endocr. Rev. 29: 535-559 [Abstract] [Full Text]  
• Canalis, E. (2008). Notch Signaling in Osteoblasts. Sci Signal 1: pe17-pe17 [Abstract] [Full Text]  
• Canalis, E., Giustina, A., Bilezikian, J. P. (2007). Mechanisms of Anabolic Therapies for Osteoporosis. NEJM 357: 905-916 [Full Text]  
• Kuznetsov, S. A., Mankani, M. H., Leet, A. I., Ziran, N., Gronthos, S., Robey, P. G. (2007). Circulating Connective Tissue Precursors: Extreme Rarity in Humans and Chondrogenic Potential in Guinea Pigs. Stem Cells 25: 1830-1839 [Abstract] [Full Text]  
• Sata, M., Tanaka, K., Nagai, R., Eghbali-Fatourechi, G. Z., Khosla, S. (2005). Circulating Osteoblast-Lineage Cells. NEJM 353: 737-738 [Full Text]