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Previous Volume 352:203-204 January 13, 2005 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Piccirillo (Aug. 26 issue)¹ recommends that acute bacterial sinusitis be treated with 500 mg of amoxicillin three times daily. Pneumococcus is an important cause of this condition and, at present, 40 percent of pneumococci in the United States have reduced susceptibility to penicillin.²

This reduced susceptibility has prompted physicians to recommend amoxicillin, 90 mg per kilogram of body weight per day in divided doses, to treat otitis media,³ and daily doses of amoxicillin ranging from 1.5 to 4 g daily for treating acute bacterial sinusitis in adults.⁴ For sinusitis, the lower dosage is recommended in geographic areas . . . [Full Text of this Article]

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