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An 80-year-old man was admitted to the hospital because of shortness of breath, pleural effusions, and edema of the legs.
Atrial fibrillation had developed seven years earlier, with bradycardia and syncope, and a pacemaker had been placed. Angina developed two and a half years before admission and was treated with three-vessel coronary-artery bypass grafting. The patient had several episodes of congestive heart failure thereafter. Eleven months before admission, urinalysis revealed 3+ proteinuria, an increase from 1+ one year earlier. Nine months before admission, a subtotal colectomy was performed because of ischemic colitis with bleeding. Bilateral pleural effusions, pulmonary edema, and
Differential Diagnosis
Causes of the Nephrotic Syndrome
Organ Dysfunction in Systemic Amyloidosis
Types of Systemic Amyloidosis
Nonamyloid Immunoglobulin Deposition Diseases
Clinical Diagnosis
Dr. Laura M. Dember's Diagnosis
Pathological Discussion
Anatomical Diagnosis
Source Information
From the Renal Section, Department of Medicine, Boston Medical Center, Boston University School of Medicine (L.M.D.); the Departments of Radiology (J.O.S.), Cardiology (F.N.), and Pathology (J.R.S.), Massachusetts General Hospital; and the Departments of Radiology (J.O.S.), Cardiology (F.N.), and Pathology (J.R.S.), Harvard Medical School all in Boston.
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