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Volume 352:2134-2135 May 19, 2005 Number 20
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Treatment of Myelodysplastic Syndromes

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 by Cazzola, M.
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 by List, A.
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To the Editor: List et al. (Feb. 10 issue)1 report encouraging results with regard to the efficacy of lenalidomide, a thalidomide analogue, in the treatment of patients with myelodysplastic syndromes and symptomatic anemia whose condition failed to respond to erythropoietin. List et al. tested three dosing regimens, but little is said about their advantages or disadvantages. It appears that the lowest dosing regimen (10 mg per day for 21 days in a 28-day cycle) produced the best response with the least toxicity, but it is unclear what the median duration of response and the number of cytogenetic responses were with . . . [Full Text of this Article]


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