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Volume 352:2245-2246 May 26, 2005 Number 21
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Surgery for Asymptomatic Mitral Regurgitation

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by Enriquez-Sarano, M.
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To the Editor: In their study of determinants of the outcome of asymptomatic mitral regurgitation, Enriquez-Sarano et al. (March 3 issue)1 concluded that patients who have an effective regurgitant orifice of at least 40 mm2 should be considered for surgery promptly. We have some concern about this conclusion, which we believe to be overstated.

In the study, 80 percent of patients had mitral-valve prolapse as the cause of mitral regurgitation, but the anatomical characteristics of the mitral valve on echocardiography were not reported. A previous study showed that patients with mitral-leaflet thickening (≥5 mm) had a risk of complications, . . . [Full Text of this Article]



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