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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.
A 10-year-old girl with atopic dermatitis reports itching that has recently become relentless, resulting in sleep loss. Her mother has been reluctant to treat the girl with topical corticosteroids, because she was told that they damage the skin, but she is exhausted and wants relief for her child. How should the problem be managed?
The Clinical Problem
Atopic dermatitis (or atopic eczema) is an itchy,
Diagnostic Criteria
Prevalence, Cost, and Prognosis
Causes
Strategies and Evidence
Diagnosis
Treatment
Topical Corticosteroids
Emollients
Topical Calcineurin Inhibitors
Other Topical Agents
Oral Antihistamines
Topical Doxepin
Antibiotic Agents
Ultraviolet Light
Immunosuppressive Agents
Nonpharmacologic Approaches
Areas of Uncertainty
Guidelines
Conclusions and Recommendations
Source Information
From the Center of Evidence-Based Dermatology, Queen's Medical Center, University of Nottingham, Nottingham, United Kingdom.
Address reprint requests to Professor Williams at the Center of Evidence-Based Dermatology, Queen's Medical Center, University of Nottingham, Nottingham NG7 2UH, United Kingdom, or at hywel.williams@nottingham.ac.uk.
Related Letters:
Atopic Dermatitis
Treloar V., Williams H. C.
Extract |
Full Text |
PDF
N Engl J Med 2005;
353:1069-1070, Sep 8, 2005.
Correspondence
This article has been cited by other articles:
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