Chemotherapy, an integral component of adjuvant treatment forwomen with resected node-positive breast cancer, improves disease-freeand overall survival in many patients. Older regimens includesuch combinations as cyclophosphamide, methotrexate, and fluorouracil;doxorubicin and cyclophosphamide; fluorouracil, doxorubicin,and cyclophosphamide given in various doses and according tovarious schedules; and fluorouracil, epirubicin, and cyclophosphamide,among others. Standards of care continue to evolve, owing tothe availability of new drugs and data from innovative clinicaltrials that have tested different combinations of existing andnew agents.
The taxanes (docetaxel and paclitaxel) have emerged as potentagents for the adjuvant treatment of early . . . [Full Text of this Article]
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