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Previous Volume 352:2376-2378 June 9, 2005 Number 23 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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About 5 percent of adults in the United States have palpable thyroid nodules. Most of these nodules are at least 2 cm in their longest dimension, and their frequency doesn't change much with age. Ultrasonography, unquestionably the most sensitive thyroid-imaging test, reveals smaller nodules in many more people, and the frequency of these nodules does increase with age. A thyroid nodule may represent any of a variety of entities (see diagram).^1,2 Among the nodules that are evaluated by biopsy, about 95 percent are benign. Since there is selection for biopsy, mostly on the basis of size (the criterion is . . . [Full Text of this Article]

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Dr. Utiger is a clinical professor of medicine at Harvard Medical School and Brigham and Women's Hospital, Boston.

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