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A 40-year-old woman presented with exertional chest pain and was found to have familial hypercholesterolemia (type IIa) and severe three-vessel coronary artery disease. Xanthoma palpebrarum was noted on physical examination, manifested as pseudospectacles (Panel A). The patient also had associated tuberous xanthomas of tumorous proportion on the buttocks, hands, and feet (Panels B and C). Her lipid profile revealed the following levels: total cholesterol, 550 mg per deciliter (14.22 mmol per liter); triglycerides, 180 mg per deciliter (2.03 mmol per liter); high-density lipoprotein cholesterol, 34 mg per deciliter (0.88 mmol per liter); and low-density lipoprotein cholesterol, 480 mg per deciliter . . . [Full Text of this Article] |
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