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A 22-year-old black woman was transferred to this hospital because of respiratory failure.
A diagnosis of sickle cell anemia had been made when the patient was a child, at six years of age. She had last been hospitalized for a sickle cell crisis 12 years earlier. One month before admission, she had bilateral arm pain after jogging and went to a local hospital. A chest radiographic study obtained with a portable unit showed no abnormalities except for bibasilar hazy opacities, which were thought to be due to overlying soft tissues. Laboratory test results are shown in Table 1. Morphine
Differential Diagnosis
ARDS
The Acute Chest Syndrome
Management of ARDS
Basic Principles
Management of Catastrophic ARDS
Lung Recruitment
Nitric Oxide
Pulmonary-Artery Catheters
Combination Therapy
Management of Respiratory Failure in the Acute Chest Syndrome
Transfusion Therapy for the Acute Chest Syndrome
Dr. Benjamin D. Medoff's Diagnosis
Pathological Discussion
Anatomical Diagnosis
Source Information
From the Pulmonary and Critical Care Unit, Center for Immunology and Inflammatory Diseases, Department of Medicine (B.D.M.), and the Departments of Radiology (J.O.S.) and Pathology (R.N.S., A.K.), Massachusetts General Hospital; and the Departments of Medicine (B.D.M.), Radiology (J.O.S.), and Pathology (R.N.S., A.K.), Harvard Medical School.
Related Letters:
Case 17-2005: Acute Chest Syndrome and ARDS
Castro O., Gladwin M. T., Kopterides P., Fremont R., Medoff B. D.
Extract |
Full Text |
PDF
N Engl J Med 2005;
353:1529-1530, Oct 6, 2005.
Correspondence
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