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Previous Volume 352:2553 June 16, 2005 Number 24 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Arad et al. (Jan. 27 issue)¹ report that LAMP2 mutations (Danon's disease) are an important cause of hypertrophic cardiomyopathy. That one of their patients had an "adolescent response to cardiac disease," however, strangely misses the point that mental retardation commonly accompanies this disease. Both of the patients in the original cases described by Danon et al.² had mental retardation, and in a series of 38 patients, described by Sugie et al.,³ 70 percent of male patients (14 of 20) and 6 percent of female patients (1 of 18) had mental retardation. Lobrinus et al.⁴ and Sugie et . . . [Full Text of this Article]

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