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A 38-year-old woman presented with increasing abdominal fullness and a new rash on the lower extremities. She had a history of chronic hepatitis C infection, for which she had been treated with interferon alfa several years earlier. She had a remote history of alcohol and intravenous drug use. On physical examination, ascites, caput medusae, spider hemangiomas, and palpable lesions on the legs and feet were noted. Laboratory evaluation revealed an albumin level of 1.0 gm per deciliter, an international normalized ratio of 2.3, the presence of cryoglobulins, a positive result on testing for hepatitis C antibody, and a negative result . . . [Full Text of this Article] |