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Volume 352:309 January 20, 2005 Number 3
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Case 29-2004: A Woman with Acute Onset of Chest Pain and Fever

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 by Karchmer, A. W.
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To the Editor: With reference to the recent Case Record (Sept. 16 issue)1 about a 75-year-old woman with acute onset of chest pain followed by fever, I would question the decision to initiate empirical levofloxacin treatment after specimens had been obtained for culture. The presentation included fever, systemic symptoms, cardiac symptoms, a murmur, and abnormal results of urinalysis in a patient with known (albeit mild) valve disease. Therefore, I would have thought that endocarditis would be at the top (or near the top) of the differential diagnosis, although the murmur was not typical of mitral regurgitation and no aortic regurgitant . . . [Full Text of this Article]




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