Merck's withdrawal of rofecoxib from the market last Septemberand Pfizer's announcement in December of possible cardiac risksassociated with high doses of celecoxib reignited long-simmeringcontroversies regarding drug promotion, in part because bothcyclooxygenase-2 inhibitors have been heavily marketed directlyto consumers. Indeed, after discussion with the Food and DrugAdministration (FDA), Pfizer suspended all direct-to-consumeradvertising of celecoxib. Adding fuel to the fire is class-actionlitigation filed against AstraZeneca alleging that its direct-to-consumeradvertising misrepresents the superiority of its proton-pumpinhibitor esomeprazole over less expensive alternatives.
Although the information made public in these cases is probablyincomplete, these . . . [Full Text of this Article]
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Dr. Berndt is a professor of applied economics at the Massachusetts Institute of Technology, Cambridge.
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