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A correction has been published: N Engl J Med 2005;352(16):1731.

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Volume 352:416-418 January 27, 2005 Number 4
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Bell's Palsy

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 by Gilden, D. H.
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To the Editor: In his Clinical Practice article on Bell's palsy, Gilden (Sept. 23 issue)1 recommends treatment of the patient in the vignette with oral prednisone. The Cochrane Collaboration2 has pointed out that the statement of the American Academy of Neurology — that early treatment with corticosteroids is "probably effective"3 — is most likely invalid because their evidence synthesis (i.e., their summary of the best available evidence) included a trial with a high rate of loss to follow-up4 and a nonrandomized trial5 — trials that both had serious threats to validity.

Without these studies, the pooled results are no longer . . . [Full Text of this Article]




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