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Previous Volume 352:905-917 March 3, 2005 Number 9 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Antithyroid drugs, which have been in use for more than half a century, remain cornerstones in the management of hyperthyroidism, especially for patients with Graves' disease. Surveys of thyroidologists from the early 1990s indicate that most practitioners consider antithyroid drugs the treatment of choice for most young people with Graves' disease, both in the United States and in the rest of the world.^1,2 A substantial amount of new information, much of it evidence-based,³ has become available since the topic was last summarized in the Journal in 1984.⁴ The present review considers recent pharmacologic and clinical data related to the use . . . [Full Text of this Article]

Pharmacology

Mechanism of Action

Clinical Pharmacology

Clinical Use of Drugs

Choice of Drugs

Practical Considerations

Remission

Discontinuation of Drug Treatment

Side Effects

Use of Antithyroid Drugs during Pregnancy and Lactation

Thyroid Storm

Summary

Source Information

From the Division of Endocrinology, Sinai Hospital of Baltimore, the Johns Hopkins University School of Medicine, Baltimore.

Address reprint requests to Dr. Cooper at the Division of Endocrinology, Sinai Hospital of Baltimore, 2401 W. Belvedere Ave., Baltimore, MD 21215, or at dcooper@lifebridgehealth.org.

Related Letters:

Antithyroid Drugs
Goichot B., Vinzio S., Lubin E., Nebesio T. D., Eugster E. A., Admiraal P. J.J., Cooper D. S.
Extract | Full Text | PDF  
N Engl J Med 2005; 352:2246-2247, May 26, 2005. Correspondence

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