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A 51-year-old woman presented with weight loss (despite good appetite), palpitations, tremor, and heat intolerance. On examination, she had typical features of Graves' disease, including a diffusely enlarged thyroid, periorbital edema, and proptosis, as well as mild thickening of the skin in the pretibial area. The diagnosis was confirmed by the results of thyroid-function tests, which showed a thyroid-stimulating hormone level of less than 0.1 mU per milliliter (normal range, 0.5 to 5.15); a triiodothyronine level of 557 ng per deciliter (8.5 nmol per liter; normal range, 100 to 190 ng [1.5 to 2.9 nmol]); and a thyroxine level of . . . [Full Text of this Article] |