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Previous Volume 353:9-11 July 7, 2005 Number 1 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Atherosclerosis is a disease of the vessel wall involving lipid accumulation, chronic inflammation, cell death, and thrombosis that causes heart disease and stroke. Although elevated cholesterol levels are a recognized risk factor for atherosclerosis, a growing number of studies suggest that oxidized phospholipids may also play an important role in this condition.^1,2 Phospholipids, essential components of lipoproteins and cell membranes, are composed of fatty acids bound to a glycerol backbone containing a polar head group. They are susceptible to free-radical or enzymatic oxidation by myeloperoxidase, lipoxygenase, and other enzymes that are present in the vessel wall. The addition of oxygen . . . [Full Text of this Article]

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Dr. Berliner is a professor of medicine and pathology and Dr. Watson is an assistant professor of medicine at the David Geffen School of Medicine, University of California, Los Angeles.

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