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Previous Volume 353:1067-1068 September 8, 2005 Number 10 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Shattuck et al. (June 9 issue)¹ demonstrate that multiple foci of papillary thyroid carcinoma are often tumors of independent clonal origins and conclude that such tumors should receive aggressive treatment. Microcarcinomas have a high prevalence in the general population² and may remain clinically silent even when they are multicentric or occur concomitantly with a clinical papillary thyroid carcinoma. Since subclinical papillary thyroid carcinoma with a low growth potential is diagnosed with increasing frequency, the problem arises for the surgeon as to whether selective treatment may be appropriate.

Multicentricity is not considered a prognostic determinant for the categorization . . . [Full Text of this Article]

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