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Correspondence
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Volume 353:1071-1072 September 8, 2005 Number 10
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Brucellosis

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 by Pappas, G.
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To the Editor: We were surprised by two omissions in the otherwise commendable review of brucellosis by Pappas and colleagues (June 2 issue).1 Without acknowledging the long-standing opinion of expert clinicians and investigators2 that Brucella melitensis causes more severe infections than does B. abortus, the authors cite a recent direct comparison3 and state that clinical severity is similar between the two strains. In contrast, our more recent analysis of brucellosis in San Diego, California,4 supports the traditional position. B. melitensis infections presented more acutely as fever of unknown origin with substantially higher rates of abdominal tenderness, hepatomegaly, splenomegaly, thrombocytopenia, pancytopenia, . . . [Full Text of this Article]




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