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A correction has been published: N Engl J Med 2006;354(2):215.

A correction has been published: N Engl J Med 2006;354(4):417.

Clinical Practice
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Volume 353:1252-1260 September 22, 2005 Number 12
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Low HDL Cholesterol Levels
M. Dominique Ashen, Ph.D., C.R.N.P., and Roger S. Blumenthal, M.D.

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 by Itskowitz, M. S.
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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors' clinical recommendations.

A 41-year-old man with dyslipidemia, hypertension, and a history of myocardial infarction four years previously comes to establish care. He is physically inactive and consumes a diet high in saturated fat. He does not smoke. Medications include a statin, a beta-blocker, an angiotensin-converting – enzyme inhibitor, and aspirin. His blood pressure is 110/80 mm Hg, and his body-mass index (the weight in . . . [Full Text of this Article]

The Clinical Problem

Strategies and Evidence

Lifestyle Modifications

            Exercise

            Smoking Cessation

            Weight Control

            Alcohol Intake

            Dietary Fat Intake

            Lifestyle and Modifying Factors

Medication

            Niacin

            Fibrates

            Statins

            Combination Therapy

Areas of Uncertainty

Guidelines from Professional Associations

Summary and Recommendations


Source Information

From the Johns Hopkins Hospital, Baltimore.

Address reprint requests to Dr. Blumenthal at Johns Hopkins Hospital, Blalock 524C, Johns Hopkins Ciccarone Preventive Cardiology Center, 600 N. Wolfe St., Baltimore, MD 21287, or at rblument@jhmi.edu


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