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Previous Volume 353:1291-1293 September 22, 2005 Number 12 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The demonstration in Tanzania of equivalent efficacy of azithromycin and penicillin G benzathine for treating early syphilis and presumed early latent syphilis (rapid plasma reagin titer, 1:8) represents a potentially useful advance in syphilis control. In a randomized trial reported in this issue of the Journal, Riedner et al.¹ achieved cure rates of 97.7 percent with 2 g of azithromycin given orally and 95.0 percent with 2.4 MU of penicillin G benzathine given intramuscularly. Positive or negative status with respect to human immunodeficiency virus (HIV) infection did not influence the results of treatment. Titers on rapid plasma reagin tests fell . . . [Full Text of this Article]

Source Information

From the Department of Medicine and the Center for AIDS and Sexually Transmitted Diseases, University of Washington, Seattle.

Related Letters:

Azithromycin versus Penicillin for Early Syphilis
Ballard R. C., Berman S. M., Fenton K. A., Savaris R. F., Abeche A. M., Klausner J. D., Kohn R. P., Kent C. K., Riedner G., Grosskurth H., Hayes R., Holmes K. K.
Extract | Full Text | PDF  
N Engl J Med 2006; 354:203-205, Jan 12, 2006. Correspondence

This article has been cited by other articles:

• Ballard, R. C., Berman, S. M., Fenton, K. A., Savaris, R. F., Abeche, A. M., Klausner, J. D., Kohn, R. P., Kent, C. K., Riedner, G., Grosskurth, H., Hayes, R., Holmes, K. K. (2006). Azithromycin versus Penicillin for Early Syphilis. NEJM 354: 203-205 [Full Text]  
• (2005). Azithromycin Might Cure Early Syphilis, but Beware of Failure. JWatch General 2005: 5-5 [Full Text]  
• (2005). Single-Dose Oral Azithromycin for Early Syphilis. JWatch Infect. Diseases 2005: 2-2 [Full Text]