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Volume 353:1300 September 22, 2005 Number 12
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Molecular Prediction of Recurrence of Breast Cancer

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 by Paik, S.
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To the Editor: The use of the Oncotype DX assay in the study reported by Paik et al. (Dec. 30 issue)1 is an example of a conflict of interest. Most of the authors of the report are employed by, receive consulting fees from, or hold equity positions or stock options in Genomic Health, the manufacturer of Oncotype DX. These authors support the adoption of a $3,000 test in lieu of information already contained in a standard surgical pathology report — the tumor grade. Table 1 of their article shows risk categories as determined by the Oncotype DX assay and the . . . [Full Text of this Article]


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