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A 38-year-old woman with a five-year history of rheumatoid arthritis had complete remission after 17 months of weekly monotherapy with 4 mg of methotrexate. Radiographs of both hands and feet were taken to assess the effectiveness of the treatment. In contrast to the radiograph that had been taken one year before the initiation of treatment (Panel A), healing of the erosions at the metatarsal head and at the base of the proximal phalanx in the fifth metatarsophalangeal joint of the right foot were observed (Panel B). The patient's symptoms in her hands, wrists, and feet (including joint pain, tenderness, swelling, . . . [Full Text of this Article] |