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Correspondence
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Volume 353:1862-1863 October 27, 2005 Number 17
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Case 22-2005: Intravenous Immune Globulin in Chronic Lymphocytic Leukemia

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by Hollander, H.
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To the Editor: Case 22-2005 (July 21 issue)1 describes an 81-year-old man with a six-year history of chronic lymphocytic leukemia (CLL) who was admitted to the hospital with cough, purulent sputum production, altered mental status, and fever (39.6°C). The serum IgG level was 310 mg per deciliter three years before admission. Instead of providing immediate immune globulin replacement on admission, his clinicians remeasured the serum IgG five days later (130 mg per deciliter), and immune globulin replacement was given seven days after admission. The patient died on the 12th hospital day.

There is an extensive body of literature supporting the . . . [Full Text of this Article]



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