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Clinical Practice
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Volume 353:1934-1944 November 3, 2005 Number 18
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Allergic Rhinitis
Marshall Plaut, M.D., and Martin D. Valentine, M.D.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors' clinical recommendations.

A Baltimore college student has rhinorrhea, sneezing, nasal congestion, and itchy, watery eyes in the spring. He reports having had similar symptoms the previous spring. Over-the-counter allergy pills have failed to help his symptoms and caused dry mouth and somnolence. He wants relief and assurance that he will not be ill, have dry mouth, or feel drowsy during final examinations. On physical . . . [Full Text of this Article]

The Clinical Problem

Strategies and Evidence

Evaluation

            History and Physical Examination

            Allergy Testing

Allergen Avoidance and Pharmacotherapies

            Allergen Avoidance

            Oral Antihistamines

            Nasal Corticosteroids

            Antihistamines Combined with Nasal Corticosteroids

            Leukotriene-Receptor Antagonists

            Mast-Cell Stabilizers

            Ophthalmic Preparations

            Intranasal Agents

            {alpha}-Adrenergic Agonists

            Systemic Corticosteroids

            Algorithm-Guided Treatment

            Allergen Immunotherapy

Areas of Uncertainty

Guidelines

Summary and Conclusions


Source Information

From the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md. (M.P.); and the Division of Allergy and Immunology, Johns Hopkins University School of Medicine, Baltimore (M.D.V.).

Address reprint requests to Dr. Plaut at the Asthma, Allergy and Inflammation Branch, Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases, 6610 Rockledge Dr., Rm. 3093, MSC-6601, Bethesda, MD 20892, or at mplaut@niaid.nih.gov.


Related Letters:

Allergic Rhinitis
Boiko P. E., Noroski L. M., Davis C., Plaut M., Valentine M. D.
Extract | Full Text | PDF  
N Engl J Med 2006; 354:1205-1206, Mar 16, 2006. Correspondence

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