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Previous Volume 353:164-171 July 14, 2005 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.

At her annual visit, a 60-year-old woman asks her physician whether she should have a bone-density test to screen for osteoporosis. The patient went through menopause at age 52 and received postmenopausal hormone therapy for four years. She takes 500 mg of calcium twice daily and exercises regularly. She has no personal history of fractures, but her mother had a hip fracture . . . [Full Text of this Article]

The Clinical Problem

Strategies and Evidence

Bone Densitometry

            Dual-Energy X-Ray Absorptiometry

            Quantitative Computed Tomography

Peripheral Measurements

Selecting Patients for Bone Densitometry

Laboratory Assessment

Areas of Uncertainty

Guidelines from Professional Societies

Summary and Recommendations

Source Information

From the Musculoskeletal Institute, University of Connecticut Health Center, Farmington.

Address reprint requests to Dr. Raisz at the Musculoskeletal Institute, University of Connecticut Health Center, 263 Farmington Ave., MC-3805, Farmington, CT 06030, or at raisz@nso.uchc.edu.

Related Letters:

Screening for Osteoporosis
Cunningham G. F., Raisz L. G.
Extract | Full Text | PDF  
N Engl J Med 2005; 353:1975, Nov 3, 2005. Correspondence

This article has been cited by other articles:

• Mayes, S. L. (2007). Review of Postmenopausal Osteoporosis Pharmacotherapy. Nutr Clin Pract 22: 276-285 [Abstract] [Full Text]  
• Khosla, S., Melton, L. J. III (2007). Osteopenia. NEJM 356: 2293-2300 [Full Text]  
• Hillier, T. A., Stone, K. L., Bauer, D. C., Rizzo, J. H., Pedula, K. L., Cauley, J. A., Ensrud, K. E., Hochberg, M. C., Cummings, S. R. (2007). Evaluating the Value of Repeat Bone Mineral Density Measurement and Prediction of Fractures in Older Women: The Study of Osteoporotic Fractures. Arch Intern Med 167: 155-160 [Abstract] [Full Text]  
• Refshauge, K M, Maher, C G (2006). Low back pain investigations and prognosis: a review. Br. J. Sports. Med. 40: 494-498 [Abstract] [Full Text]  
• Cunningham, G. F., Raisz, L. G. (2005). Screening for osteoporosis.. NEJM 353: 1975-1975 [Full Text]  
• Rosen, C. J. (2005). Postmenopausal Osteoporosis. NEJM 353: 595-603 [Full Text]