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A four-week-old male infant was admitted to this hospital because of jaundice, hyperbilirubinemia, thrombocytopenia, and abdominal distention.
The patient was born at term at another hospital by spontaneous vaginal delivery to a 37-year-old woman (gravida 2, para 2) after an uncomplicated pregnancy. Prenatal screening revealed that the mother had type A Rh-positive blood. Tests for hepatitis B surface antigen and group B streptococcus were negative. The mother was immune to rubella, and a rapid plasma reagin test was nonreactive. Before the delivery, decreased variability was noted on the fetal-heart tracing. At delivery, the infant was limp, cyanotic, apneic, and without
Differential Diagnosis
Metabolic Causes of Neonatal Hemochromatosis
Maternal Conditions Associated with Neonatal Hemochromatosis
Primary Abnormalities of Iron Homeostasis
Clinical Diagnosis
Dr. Nancy Andrews's Diagnosis
Pathological Discussion
Anatomical Diagnosis
Source Information
From the Department of Pediatrics, Children's Hospital (N.C.A.); the Departments of Radiology (S.A.) and Pathology (K.B.), Massachusetts General Hospital; and the Departments of Pediatrics (N.C.A.), Radiology (S.A.), and Pathology (K.B.), Harvard Medical School all in Boston.
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