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Previous Volume 353:205-206 July 14, 2005 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: A well-designed study aimed at showing the effect of cardiac resynchronization on mortality among patients with cardiac dyssynchrony, the Cardiac Resynchronization–Heart Failure (CARE-HF) Study (April 14 issue),¹ demonstrated improvements in quality of life and survival well beyond those expected. The question remains as to whether these patients should receive a combination device with both cardioversion and defibrillation capabilities.²

Conclusions drawn from a randomized study are very sensitive to the characteristics of the studied population. In CARE-HF, 62 percent of the patients had nonischemic cardiomyopathy. This high percentage raises the question of the generalizability of the results. In . . . [Full Text of this Article]

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