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Volume 353:211 July 14, 2005 Number 2
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Atherothrombosis and Coronary Artery Disease

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Second edition. Edited by Valentin Fuster, Eric J. Topol, and Elizabeth G. Nabel. 1636 pp., illustrated. Philadelphia, Lippincott Williams & Wilkins, 2005. $149. ISBN 0-7817-3583-1.

Most of us walk around oblivious to the time bombs that line our arteries. Indeed, atherosclerosis is, for the most part, a rather benign condition that affects, to some degree, virtually all the adult population both in developed countries and in many developing countries. Many adults will die from other causes before atherosclerosis causes overt problems. If the plaque is big enough and sitting in a coronary artery, it may impede blood flow and cause symptoms of angina. But if it is small, the plaque will usually be asymptomatic until the moment it supports thrombosis. The central role of thrombosis . . . [Full Text of this Article]




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