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Previous Volume 353:212 July 14, 2005 Number 2 Next

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Edited by Levon Michael Khachigian. 208 pp., illustrated. Boca Raton, Fla., CRC Press, 2005. $99.95. ISBN 0-8493-3028-9.

The fact that cardiovascular disease, for the most part due to atherosclerosis, is the principal killer in Western societies is well known. However, how and why atherosclerotic plaques that develop over many decades rupture in an often unheralded manner — triggering the clinical presentation of an acute coronary syndrome — is still puzzling. High-Risk Atherosclerotic Plaques addresses this problem in a wide-ranging manner with chapters that follow a rational sequence, unfolding the processes involved in plaque rupture, reviewing the efforts to develop animal models of the phenomenon, explaining the different methods devised to identify and study vulnerable plaques, and summarizing . . . [Full Text of this Article]

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