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Editorial
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Volume 353:2187-2189 November 17, 2005 Number 20
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Pharmacotherapy for Obesity — Promise and Uncertainty
Susan Z. Yanovski, M.D.

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-PubMed Citation
In 2005, a majority of adult Americans are overweight or obese,1 putting millions of them at increased risk for serious medical conditions, including cardiovascular disease, type 2 diabetes mellitus, and certain forms of cancer. In obesity, a weight loss of 5 to 10 percent can significantly improve risk factors for obesity-related diseases2 and delay or prevent type 2 diabetes in persons at high risk.3 Behavioral treatments can result in a weight loss sufficient to improve health for many patients, but often the weight is regained over time.4 Although for many people a reduction in weight is difficult to achieve, maintaining . . . [Full Text of this Article]


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From the Division of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Md.


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