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Previous Volume 353:2215-2217 November 24, 2005 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Neuroblastoma stands out among childhood cancers because of its relative frequency, enigmatic natural history, intriguing biologic features, and daunting therapeutic challenges. Much that is novel and on the cutting edge in oncology comes together in neuroblastoma: preventive screening, biology-driven management, dose-intensive or dose-dense chemotherapy, stem-cell transplantation, targeted therapies (radiation, monoclonal antibodies, drugs), agents that induce differentiation, and monitoring of minimal disease.¹

Neuroblastoma is an embryonic neoplasm of the sympathetic nervous system. The histologic composition varies from primitive cells without neuronal features to mature neurons or ganglion cells, often within the same mass. Neuroblastoma is the most common extracranial solid tumor . . . [Full Text of this Article]

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Drs. Kushner and Cheung are attending physicians in the Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York.

This article has been cited by other articles:

• Refaat, M. M., Idriss, S. Z., Blaszkowsky, L. S. (2008). Case Report: An Unusual Case of Adrenal Neuroblastoma in Pregnancy. The Oncologist 13: 152-156 [Abstract] [Full Text]