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Review Article
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Volume 353:2262-2269 November 24, 2005 Number 21
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Basal-Cell Carcinoma
Adam I. Rubin, M.D., Elbert H. Chen, M.D., and Désirée Ratner, M.D.

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According to the American Cancer Society, skin cancer is the most common cancer, accounting for about half of all cancers in the United States. More than 1 million cases of skin cancer will be diagnosed in the United States this year.1 Basal-cell carcinomas constitute approximately 80 percent of all nonmelanoma skin cancers. This article addresses cutaneous basal-cell carcinoma, which should be differentiated from the uncommon basal-cell carcinoma or basaloid carcinoma that arises in sites such as the prostate, pancreas, lung, cervix, salivary gland, thymus, and anal canal.

Incidence

The absolute incidence of basal-cell carcinoma is difficult to determine, since nonmelanoma skin . . . [Full Text of this Article]

Risk Factors

Clinical Presentation and Histologic Appearance

Molecular Pathogenesis

Features Associated with Recurrence and Metastasis

Treatment

Prevention


Source Information

From the Department of Dermatology, Columbia University, New York.

Drs. Rubin and Chen contributed equally to this article.

Address reprint requests to Dr. Ratner at the Department of Dermatology, Columbia University, 161 Fort Washington Ave., 12th Fl., New York, NY 10032, or at dr221@columbia.edu.


Related Letters:

Basal-Cell Carcinoma
De Giorgi V., Massi D., Lotti T., Mueller H., Eisendle K., Fritsch P., Rubin A. I., Chen E. H., Ratner D.
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N Engl J Med 2006; 354:769-771, Feb 16, 2006. Correspondence

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