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Editorial
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Volume 353:2394-2396 December 1, 2005 Number 22
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Rejection — More Than the Eye Can See
Terry B. Strom, M.D.

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-Related Article
 by Muthukumar, T.
-PubMed Citation
In comparing current clinical outcomes in renal transplantation with those of 30 years ago,1 graft failure from immunologic factors and death from opportunistic infection in the first year after transplantation are no longer common clinical outcomes. The therapeutic regimens used today to prevent and treat rejection or infection among renal-transplant recipients bear only a small resemblance to those used 30 years ago.

In contrast, the diagnostic strategies used to detect rejection and distinguish it from other causes of renal dysfunction have not budged during the past two decades. A rise in the level of serum creatinine suggests allograft dysfunction, but . . . [Full Text of this Article]


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From the Harvard Medical School, Beth Israel Deaconess Medical Center, Boston.


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