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Previous Volume 353:2403-2404 December 1, 2005 Number 22 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: The article by Zhang et al. (Aug. 25 issue)¹ demonstrated the usefulness of treatment of early pregnancy failure with intravaginal misoprostol but did not describe the serious complications that can arise from such administration of this drug. Although endometritis requiring hospitalization was rare in the study by Zhang et al., the Centers for Disease Control and Prevention² and Fischer et al. (in this issue of the Journal)³ have reported that five women died of toxic shock after endometrial infection with Clostridium sordellii in the United States and Canada after medical abortions with mifepristone and intravaginal misoprostol.

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