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Previous Volume 353:2510-2511 December 8, 2005 Number 23 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Wills et al. (Sept. 1 issue)¹ recently described a study of three fluid solutions, including 6 percent dextran 70, for resuscitation of children with the dengue shock syndrome. The authors observed a high rate of allergic-type reactions (fever without cardiorespiratory compromise) to dextran 70, suggesting that hydroxyethyl starch may be a preferable treatment.

Although such reactions are not true allergic events, they raise the issue of safety with dextran solutions. Severe dextran-induced anaphylactoid reactions have been well recognized since the 1970s. Fortunately, dextran 1 (Promit) usually prevents such reactions. When it is administered immediately before dextran 40 . . . [Full Text of this Article]

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