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Previous Volume 353:2637-2639 December 22, 2005 Number 25 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Eleven years after the first long-acting beta-agonist, salmeterol, was approved for sale in the United States, the Food and Drug Administration (FDA) has issued a stern public health advisory alerting "health care professionals and patients that these medicines may increase the chance of severe asthma episodes, and death when those episodes occur" (www.fda.gov/cder/drug/advisory/LABA.htm). The announcement followed a July 2005 meeting of an FDA advisory committee on this topic. What are the consequences of this advisory for the treatment of asthma?

Currently, inhaled corticosteroids are the most effective treatment for the symptoms of persistent asthma. However, in patients with . . . [Full Text of this Article]

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Dr. Martinez is a professor of pediatrics and director of the Arizona Respiratory Center, University of Arizona College of Medicine, Tucson.

Related Letters:

Safety of Long-Acting Beta-Agonists
Mintz M. L., O'Connor G. T., Martinez F. D.
Extract | Full Text | PDF  
N Engl J Med 2006; 354:1206-1208, Mar 16, 2006. Correspondence

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